LIVE · 522 PROCEDURES · 591 CLINICS
✦ PROTOCOL · NO 09

Diabetes,
two ways.

An A1c that crept past 5.7. Morning numbers that won’t come down. A family history you can feel coming, or a diagnosis already in the chart. On the left, the standard-of-care workup: diagnosis, metformin, GLP-1s, monitoring. On the right, the metabolic and lifestyle protocol aimed at remission, alongside the meds, not instead.

A1c lab report + finger-prick test
1 IN 3 · US ADULTS PREDIABETIC
2 TRACKS · 10 STEPS
UPDATED MAY 2026
TRACK · A · conventional

Conventional medicine

Type 2 diabetes is diagnosed, staged, and treated against A1c targets. Standard-of-care meds (metformin, GLP-1s, SGLT2s, insulin) have strong outcome data for heart, kidney, and eye complications.

TRACK · B · metabolic

Metabolic / lifestyle

Type 2 diabetes is largely a disease of insulin resistance, body composition, and food environment. The lifestyle track aims at remission or major dose-reduction, alongside meds, not instead of them, and never without a clinician on board.

Week 0
Diagnosis + baseline labs

Confirm with two of: fasting glucose ≥126, A1c ≥6.5, or OGTT ≥200. Baseline CMP, lipids, urine albumin, foot exam, dilated eye referral. Stage as prediabetes / T2DM.

$80-$220 PCP · $39-$95 tele · Family MD · internist
Day 0
KEEP YOUR TEAM

Never stop insulin, sulfonylureas, or SGLT2s without supervision, hypoglycemia and DKA risk. Tell your prescriber you’re changing diet so doses get adjusted. This page is for adjunct lifestyle work, not replacement of care.

$80-$520 visit · PCP / endo · non-negotiable
Week 1-4
First-line therapy

Metformin titrated to 1,000-2,000 mg / day. Add GLP-1 (semaglutide, tirzepatide) for A1c >8 or BMI ≥27. SGLT2 if CKD or CVD. Statin per ASCVD score. ACE inhibitor if microalbuminuria.

$4-$40 / mo metformin · $25-$1,300 / mo GLP-1 · PCP · endocrinology
Week 1-4
Carb quality + protein floor

Cut liquid sugar and ultra-processed carbs first. Build meals around 30-40 g protein + non-starchy vegetables + healthy fat. Many do well with <100 g carb / day; some go lower-carb / ketogenic under supervision.

$110-$220 RD visit · Registered dietitian · Dr. Jason Fung · Dr. Mark Hyman
Month 1-3
CGM + glucose monitoring

Continuous glucose monitor (Dexcom, Libre) for 2-4 weeks, then ongoing for insulin users. Otherwise fingerstick fasting + post-meal. Targets: fasting 80-130, 2-hr postprandial <180.

$80-$340 / mo CGM · $10-$40 / mo strips · PCP · pharmacy
Week 2-8
Walk after meals + Zone-2

10-20 min walk after each main meal (the highest-leverage glucose intervention there is). 3 × 30-45 min Zone-2 cardio / wk. Build to 7-10k steps daily.

$0-$120 / mo gym · Self · Dr. Peter Attia
Month 3-12
Intensify + complication screen

A1c every 3 mo. Stack therapy if >7%: add basal insulin, switch / add GLP-1. Annual: dilated eye exam, foot exam, urine albumin, lipids. Cardiology if ASCVD.

$220-$520 endo visit · $140-$320 retinal screen · Endocrinology · ophthalmology · podiatry
Week 4-16
Strength + body composition

2-3 × wk full-body strength training. Muscle is the largest glucose sink in the body. Aim for 5-10% bodyweight loss if BMI ≥27, the single strongest predictor of remission.

$60-$140 / session trainer · Trainer or self · Dr. Gabrielle Lyon
Year 1+
Long-term management

A1c · 2-4 × yr. Annual complication screen. Vaccines (flu, pneumococcal, RSV, shingles, hepatitis B). Mental-health check, diabetes-related distress is common and undertreated.

$180-$420 / visit · PCP · multidisciplinary team
Ongoing
Sleep + stress + measurement

Sleep 7-9 hr, short sleep alone raises insulin resistance ~25%. Stress / cortisol management. Use CGM data to see your personal trigger foods. Re-check A1c every 3 mo.

$80-$340 / mo CGM · Self · CGM · therapist if needed
✦ THE METABOLIC SOURCES

Who built
track B.

All four sources are MDs or DOs. Track B is the lifestyle scaffolding to run alongside your prescribing clinician, dose adjustments stay with them.

CONVENTIONAL MEDICINE · SOURCES
  • ADA Standards of Care 2026Guidelines
  • UKPDS / DCCT long-term follow-upRCT cohort
  • AACE Comprehensive AlgorithmSpecialty body
METABOLIC / LIFESTYLE · SOURCES
  • DiRECT trial · dietary remission of T2DMRCT
  • Virta Health · 5-yr remission cohortClinical cohort
  • Dr. Jason Fung · The Diabetes CodeNephrologist · author
  • Dr. Peter Attia · OutliveMD · author